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Cancer cells educate natural killer cells to a metastasis-promoting cell state
Natural killer (NK) cells have potent antitumor and antimetastatic activity. It is incompletely understood how cancer cells escape NK cell surveillance. Using ex vivo and in vivo models of metastasis, we establish that keratin-14(+) breast cancer cells are vulnerable to NK cells. We then discovered...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480097/ https://www.ncbi.nlm.nih.gov/pubmed/32645139 http://dx.doi.org/10.1083/jcb.202001134 |