Cancer cells educate natural killer cells to a metastasis-promoting cell state

Natural killer (NK) cells have potent antitumor and antimetastatic activity. It is incompletely understood how cancer cells escape NK cell surveillance. Using ex vivo and in vivo models of metastasis, we establish that keratin-14(+) breast cancer cells are vulnerable to NK cells. We then discovered...

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Detalles Bibliográficos
Autores principales: Chan, Isaac S., Knútsdóttir, Hildur, Ramakrishnan, Gayathri, Padmanaban, Veena, Warrier, Manisha, Ramirez, Juan Carlos, Dunworth, Matthew, Zhang, Hao, Jaffee, Elizabeth M., Bader, Joel S., Ewald, Andrew Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480097/
https://www.ncbi.nlm.nih.gov/pubmed/32645139
http://dx.doi.org/10.1083/jcb.202001134

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