Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy

Damaged mitochondria are selectively eliminated in a process called mitophagy. Parkin and PINK1, proteins mutated in Parkinson’s disease, amplify ubiquitin signals on damaged mitochondria with the subsequent activation of autophagic machinery. Autophagy adaptors are thought to link ubiquitinated mit...

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Detalles Bibliográficos
Autores principales: Yamano, Koji, Kikuchi, Reika, Kojima, Waka, Hayashida, Ryota, Koyano, Fumika, Kawawaki, Junko, Shoda, Takuji, Demizu, Yosuke, Naito, Mikihiko, Tanaka, Keiji, Matsuda, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480101/
https://www.ncbi.nlm.nih.gov/pubmed/32556086
http://dx.doi.org/10.1083/jcb.201912144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480101/
https://www.ncbi.nlm.nih.gov/pubmed/32556086
http://dx.doi.org/10.1083/jcb.201912144

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