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The kinesin-like protein Pavarotti functions noncanonically to regulate actin dynamics

Pavarotti, the Drosophila MKLP1 orthologue, is a kinesin-like protein that works with Tumbleweed (MgcRacGAP) as the centralspindlin complex. This complex is essential for cytokinesis, where it helps to organize the contractile actomyosin ring at the equator of dividing cells by activating the RhoGEF...

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Detalles Bibliográficos
Autores principales: Nakamura, Mitsutoshi, Verboon, Jeffrey M., Prentiss, Clara L., Parkhurst, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480107/
https://www.ncbi.nlm.nih.gov/pubmed/32673395
http://dx.doi.org/10.1083/jcb.201912117