Cargando…
Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia
Tumor cells exposed to a physiological matrix of type I collagen fibers form elongated collagenolytic invadopodia, which differ from dotty-like invadopodia forming on the gelatin substratum model. The related scaffold proteins, TKS5 and TKS4, are key components of the mechanism of invadopodia assemb...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480108/ https://www.ncbi.nlm.nih.gov/pubmed/32673397 http://dx.doi.org/10.1083/jcb.201910132 |