Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia

Tumor cells exposed to a physiological matrix of type I collagen fibers form elongated collagenolytic invadopodia, which differ from dotty-like invadopodia forming on the gelatin substratum model. The related scaffold proteins, TKS5 and TKS4, are key components of the mechanism of invadopodia assemb...

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Detalles Bibliográficos
Autores principales: Zagryazhskaya-Masson, Anna, Monteiro, Pedro, Macé, Anne-Sophie, Castagnino, Alessia, Ferrari, Robin, Infante, Elvira, Duperray-Susini, Aléria, Dingli, Florent, Lanyi, Arpad, Loew, Damarys, Génot, Elisabeth, Chavrier, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480108/
https://www.ncbi.nlm.nih.gov/pubmed/32673397
http://dx.doi.org/10.1083/jcb.201910132

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