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Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion

Cancer is characterized by genomic instability leading to deletion or amplification of oncogenes or tumor suppressors. However, most of the altered regions are devoid of known cancer drivers. Here, we identify lncRNAs frequently lost or amplified in cancer. Among them, we found amplified lncRNA asso...

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Detalles Bibliográficos
Autores principales: Athie, Alejandro, Marchese, Francesco P., González, Jovanna, Lozano, Teresa, Raimondi, Ivan, Juvvuna, Prasanna Kumar, Abad, Amaya, Marin-Bejar, Oskar, Serizay, Jacques, Martínez, Dannys, Ajona, Daniel, Pajares, Maria Jose, Sandoval, Juan, Montuenga, Luis M., Kanduri, Chandrasekhar, Lasarte, Juan J., Huarte, Maite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480115/
https://www.ncbi.nlm.nih.gov/pubmed/32858747
http://dx.doi.org/10.1083/jcb.201908078