Epigenetic modulation of the MAPK pathway prevents isoflurane-induced neuronal apoptosis and cognitive decline in aged rats

Isoflurane is a broadly used inhalation anesthetic that causes cognitive impairment in rodent models as well as humans. Although previous studies suggested an association between isoflurane exposure and neuro-inflammation, apoptosis and mitochondrial dysfunction, the pathogenesis of isoflurane-induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Lei, Fang, Hai-Bin, Cheng, Hui-Hui, Mei, Sheng-Lan, Cheng, Yun-Ping, Lv, Yao, Meng, Qing-Tao, Xia, Zhong-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480129/
https://www.ncbi.nlm.nih.gov/pubmed/32952626
http://dx.doi.org/10.3892/etm.2020.9162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480129/
https://www.ncbi.nlm.nih.gov/pubmed/32952626
http://dx.doi.org/10.3892/etm.2020.9162

Ejemplares similares