IGF-1 induces cellular senescence in rat articular chondrocytes via Akt pathway activation

Cellular senescence decreases cell proliferation over time and is characterized by typical markers, including larger cell volume, a flattened morphology, irreversible cell cycle arrest, augmentation of senescence-associated β-galactosidase (SA-β-gal) activity and senescence-associated secretory phen...

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Detalles Bibliográficos
Autores principales: Zhao, Li-Dong, Bie, Lian-Yu, Hu, Lan, Zhu, Zi-Han, Meng, Xing-Hua, Cong, Lin-Lin, Zhang, Shai, Ma, Ning, Xiao, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480142/
https://www.ncbi.nlm.nih.gov/pubmed/32952639
http://dx.doi.org/10.3892/etm.2020.9177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480142/
https://www.ncbi.nlm.nih.gov/pubmed/32952639
http://dx.doi.org/10.3892/etm.2020.9177

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