Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium

Either caspase-1 or caspase-11 can cleave gasdermin D to cause pyroptosis, eliminating intracellular replication niches. We previously showed that macrophages detect Burkholderia thailandensis via NLRC4, triggering the release of interleukin (IL)-18 and driving an essential interferon (IFN)-γ respon...

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Detalles Bibliográficos
Autores principales: Kovacs, Stephen B., Oh, Changhoon, Maltez, Vivien I., McGlaughon, Benjamin D., Verma, Ambika, Miao, Edward A., Aachoui, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480168/
https://www.ncbi.nlm.nih.gov/pubmed/32726630
http://dx.doi.org/10.1016/j.celrep.2020.107967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480168/
https://www.ncbi.nlm.nih.gov/pubmed/32726630
http://dx.doi.org/10.1016/j.celrep.2020.107967

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