Cargando…
Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
Either caspase-1 or caspase-11 can cleave gasdermin D to cause pyroptosis, eliminating intracellular replication niches. We previously showed that macrophages detect Burkholderia thailandensis via NLRC4, triggering the release of interleukin (IL)-18 and driving an essential interferon (IFN)-γ respon...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480168/ https://www.ncbi.nlm.nih.gov/pubmed/32726630 http://dx.doi.org/10.1016/j.celrep.2020.107967 |