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Expanded toolbox for directing the biosynthesis of macrocyclic peptides in bacterial cells

The macrocyclization of recombinant polypeptides by means of genetically encodable non-canonical amino acids has recently provided an attractive strategy for the screening and discovery of macrocyclic peptide inhibitors of protein–protein interactions. Here, we report the development of an expanded...

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Detalles Bibliográficos
Autores principales: Iannuzzelli, Jacob A., Fasan, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480269/
https://www.ncbi.nlm.nih.gov/pubmed/32953014
http://dx.doi.org/10.1039/d0sc01699c

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