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Expanded toolbox for directing the biosynthesis of macrocyclic peptides in bacterial cells
The macrocyclization of recombinant polypeptides by means of genetically encodable non-canonical amino acids has recently provided an attractive strategy for the screening and discovery of macrocyclic peptide inhibitors of protein–protein interactions. Here, we report the development of an expanded...
Autores principales: | Iannuzzelli, Jacob A., Fasan, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480269/ https://www.ncbi.nlm.nih.gov/pubmed/32953014 http://dx.doi.org/10.1039/d0sc01699c |
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