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Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors. Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not been explored....

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Detalles Bibliográficos
Autores principales: Whittaker, Thomas E., Nagelkerke, Anika, Nele, Valeria, Kauscher, Ulrike, Stevens, Molly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480412/
https://www.ncbi.nlm.nih.gov/pubmed/32944192
http://dx.doi.org/10.1080/20013078.2020.1807674