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A Highly Polarized Th2 Bladder Response to Infection Promotes Epithelial Repair at the Expense of Preventing New Infections

Urinary tract infections (UTIs) typically evoke prompt and vigorous innate bladder immune responses including extensive exfoliation of the epithelium. To explain the basis for the extraordinarily high recurrence rates of UTIs, we examined adaptive immune responses in mouse bladders. We found that fo...

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Detalles Bibliográficos
Autores principales: Wu, Jianxuan, Hayes, Byron W., Phoenix, Cassandra, Macias, Gustavo Sosa, Miao, Yuxuan, Choi, Hae Woong, Hughes, Francis M., Purves, J. Todd, Reinhardt, R. Lee, Abraham, Soman N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480508/
https://www.ncbi.nlm.nih.gov/pubmed/32424366
http://dx.doi.org/10.1038/s41590-020-0688-3