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Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling

Exosomes (Exo)-based therapy holds promise for treatment of lethal pancreatic cancer (PC). Limited understanding of key factors affecting Exo uptake in PC cells restricts better design of Exo-based therapy. This work aims to study the uptake properties of different Exo by PC cells. Exo from pancreat...

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Detalles Bibliográficos
Autores principales: Xu, Lizhou, Faruqu, Farid N., Liam-or, Revadee, Abu Abed, Omar, Li, Danyang, Venner, Kerrie, Errington, Rachel J, Summers, Huw, Wang, Julie Tzu-Wen, Al-Jamal, Khuloud T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480572/
https://www.ncbi.nlm.nih.gov/pubmed/32944169
http://dx.doi.org/10.1080/20013078.2020.1779458