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Increased small extracellular vesicle secretion after chemotherapy via upregulation of cholesterol metabolism in acute myeloid leukaemia

Most patients with acute myeloid leukaemia (AML) experience disease recurrence after chemotherapy largely due to the development of drug resistance. Small extracellular vesicles (sEVs) are known to play a significant role in leukaemia drug resistance by delivery of anti-apoptotic proteins and genes...

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Detalles Bibliográficos
Autores principales: Hong, Chang-Sook, Jeong, Emily, Boyiadzis, Michael, Whiteside, Theresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480590/
https://www.ncbi.nlm.nih.gov/pubmed/32944189
http://dx.doi.org/10.1080/20013078.2020.1800979