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Actin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes

T-cell receptor stimulation induces the convergence of multivesicular bodies towards the microtubule-organizing centre (MTOC) and the polarization of the MTOC to the immune synapse (IS). These events lead to exosome secretion at the IS. We describe here that upon IS formation centrosomal area F-acti...

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Detalles Bibliográficos
Autores principales: Bello-Gamboa, Ana, Velasco, Marta, Moreno, Solange, Herranz, Gonzalo, Ilie, Roxana, Huetos, Silvia, Dávila, Sergio, Sánchez, Alicia, Bernardino De La Serna, Jorge, Calvo, Víctor, Izquierdo, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480611/
https://www.ncbi.nlm.nih.gov/pubmed/32939232
http://dx.doi.org/10.1080/20013078.2020.1759926