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Determining the interaction status and evolutionary fate of duplicated homomeric proteins

Oligomeric proteins are central to life. Duplication and divergence of their genes is a key evolutionary driver, also because duplications can yield very different outcomes. Given a homomeric ancestor, duplication can yield two paralogs that form two distinct homomeric complexes, or a heteromeric co...

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Detalles Bibliográficos
Autores principales: Mallik, Saurav, Tawfik, Dan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480870/
https://www.ncbi.nlm.nih.gov/pubmed/32853212
http://dx.doi.org/10.1371/journal.pcbi.1008145