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Determining the interaction status and evolutionary fate of duplicated homomeric proteins
Oligomeric proteins are central to life. Duplication and divergence of their genes is a key evolutionary driver, also because duplications can yield very different outcomes. Given a homomeric ancestor, duplication can yield two paralogs that form two distinct homomeric complexes, or a heteromeric co...
Autores principales: | Mallik, Saurav, Tawfik, Dan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480870/ https://www.ncbi.nlm.nih.gov/pubmed/32853212 http://dx.doi.org/10.1371/journal.pcbi.1008145 |
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