Demyelination in hereditary sensory neuropathy type‐1C

OBJECTIVE: Sphingolipids are enriched in the nerves. Serine‐palmitoyltransferase (SPT) catalyzes the key step of sphingolipids biosynthesis. Mutations in SPT subunits (SPTLC) lead to the excessive production of neurotoxic deoxysphingolipids (DoxSLs) in patients with Hereditary Sensory Neuropathy Typ...

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Detalles Bibliográficos
Autores principales: Saba, Sadaf, Chen, Yongsheng, Maddipati, Krishna Rao, Hackett, Melody, Hu, Bo, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480917/
https://www.ncbi.nlm.nih.gov/pubmed/32730653
http://dx.doi.org/10.1002/acn3.51110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480917/
https://www.ncbi.nlm.nih.gov/pubmed/32730653
http://dx.doi.org/10.1002/acn3.51110

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