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Comparing progression biomarkers in clinical trials of early Alzheimer’s disease

OBJECTIVE: To investigate the statistical power of plasma, imaging, and cognition biomarkers as Alzheimer’s disease (AD) clinical trial outcome measures. METHODS: Plasma neurofilament light, structural magnetic resonance imaging, and cognition were measured longitudinally in the Alzheimer’s Disease...

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Detalles Bibliográficos
Autores principales: Cullen, Nicholas C., Zetterberg, Henrik, Insel, Philip S., Olsson, Bob, Andreasson, Ulf, Blennow, Kaj, Hansson, Oskar, Mattsson‐Carlgren, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480920/
https://www.ncbi.nlm.nih.gov/pubmed/32779869
http://dx.doi.org/10.1002/acn3.51158