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A graph-based approach identifies dynamic H-bond communication networks in spike protein S of SARS-CoV-2

Corona virus spike protein S is a large homo-trimeric protein anchored in the membrane of the virion particle. Protein S binds to angiotensin-converting-enzyme 2, ACE2, of the host cell, followed by proteolysis of the spike protein, drastic protein conformational change with exposure of the fusion p...

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Detalles Bibliográficos
Autores principales: Karathanou, Konstantina, Lazaratos, Michalis, Bertalan, Éva, Siemers, Malte, Buzar, Krzysztof, Schertler, Gebhard F.X., del Val, Coral, Bondar, Ana-Nicoleta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481144/
https://www.ncbi.nlm.nih.gov/pubmed/32919067
http://dx.doi.org/10.1016/j.jsb.2020.107617