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A graph-based approach identifies dynamic H-bond communication networks in spike protein S of SARS-CoV-2
Corona virus spike protein S is a large homo-trimeric protein anchored in the membrane of the virion particle. Protein S binds to angiotensin-converting-enzyme 2, ACE2, of the host cell, followed by proteolysis of the spike protein, drastic protein conformational change with exposure of the fusion p...
Autores principales: | Karathanou, Konstantina, Lazaratos, Michalis, Bertalan, Éva, Siemers, Malte, Buzar, Krzysztof, Schertler, Gebhard F.X., del Val, Coral, Bondar, Ana-Nicoleta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481144/ https://www.ncbi.nlm.nih.gov/pubmed/32919067 http://dx.doi.org/10.1016/j.jsb.2020.107617 |
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