CHIP as a therapeutic target for neurological diseases

Carboxy-terminus of Hsc70-interacting protein (CHIP) functions both as a molecular co-chaperone and ubiquitin E3 ligase playing a critical role in modulating the degradation of numerous chaperone-bound proteins. To date, it has been implicated in the regulation of numerous biological functions, incl...

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Detalles Bibliográficos
Autores principales: Zhang, Shuo, Hu, Zheng-wei, Mao, Cheng-yuan, Shi, Chang-he, Xu, Yu-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481199/
https://www.ncbi.nlm.nih.gov/pubmed/32908122
http://dx.doi.org/10.1038/s41419-020-02953-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481199/
https://www.ncbi.nlm.nih.gov/pubmed/32908122
http://dx.doi.org/10.1038/s41419-020-02953-5

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