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CHIP as a therapeutic target for neurological diseases
Carboxy-terminus of Hsc70-interacting protein (CHIP) functions both as a molecular co-chaperone and ubiquitin E3 ligase playing a critical role in modulating the degradation of numerous chaperone-bound proteins. To date, it has been implicated in the regulation of numerous biological functions, incl...
Autores principales: | Zhang, Shuo, Hu, Zheng-wei, Mao, Cheng-yuan, Shi, Chang-he, Xu, Yu-ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481199/ https://www.ncbi.nlm.nih.gov/pubmed/32908122 http://dx.doi.org/10.1038/s41419-020-02953-5 |
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