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A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex

Hydrogen peroxide (H(2)O(2)) is recognized to act as a signaling molecule. Peroxiredoxins (Prxs) have the ability to transfer H(2)O(2)-derived oxidizing equivalents to redox-regulated target proteins, thus facilitating the transmission of H(2)O(2) signals. It has remained unclear how Prxs and their...

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Detalles Bibliográficos
Autores principales: Talwar, Deepti, Messens, Joris, Dick, Tobias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481202/
https://www.ncbi.nlm.nih.gov/pubmed/32908147
http://dx.doi.org/10.1038/s41467-020-18324-9