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A miR-210-3p regulon that controls the Warburg effect by modulating HIF-1α and p53 activity in triple-negative breast cancer

Reprogrammed energy metabolism, especially the Warburg effect (aerobic glycolysis), is an emerging hallmark of cancer. Different from other breast cancer subtypes, triple-negative breast cancer (TNBC) exhibits high metabolic remodeling, increased aggressiveness and lack of targeted therapies. MicroR...

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Detalles Bibliográficos
Autores principales: Du, Ye, Wei, Na, Ma, Ruolin, Jiang, Shuheng, Song, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481213/
https://www.ncbi.nlm.nih.gov/pubmed/32908121
http://dx.doi.org/10.1038/s41419-020-02952-6