Post-GWAS knowledge gap: the how, where, and when

Genetic risk for complex diseases very rarely reflects only Mendelian-inherited phenotypes where single-gene mutations can be followed in families by linkage analysis. More commonly, a large set of low-penetrance, small effect-size variants combine to confer risk; they are normally revealed in genom...

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Detalles Bibliográficos
Autores principales: Pierce, Steven E., Booms, Alix, Prahl, Jordan, van der Schans, Edwin J. C., Tyson, Trevor, Coetzee, Gerhard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481221/
https://www.ncbi.nlm.nih.gov/pubmed/32964108
http://dx.doi.org/10.1038/s41531-020-00125-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481221/
https://www.ncbi.nlm.nih.gov/pubmed/32964108
http://dx.doi.org/10.1038/s41531-020-00125-y

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