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Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic acid (ARA), play fundamental roles in mammalian physiology. Although PUFA imbalance causes various disorders, mechanisms of the regulation of their systemic levels are poorly understood. Here, we report that hepa...

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Detalles Bibliográficos
Autores principales: Hishikawa, Daisuke, Yanagida, Keisuke, Nagata, Katsuyuki, Kanatani, Ayumi, Iizuka, Yoshiko, Hamano, Fumie, Yasuda, Megumi, Okamura, Tadashi, Shindou, Hideo, Shimizu, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481256/
https://www.ncbi.nlm.nih.gov/pubmed/32891885
http://dx.doi.org/10.1016/j.isci.2020.101495