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Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids
Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic acid (ARA), play fundamental roles in mammalian physiology. Although PUFA imbalance causes various disorders, mechanisms of the regulation of their systemic levels are poorly understood. Here, we report that hepa...
Autores principales: | Hishikawa, Daisuke, Yanagida, Keisuke, Nagata, Katsuyuki, Kanatani, Ayumi, Iizuka, Yoshiko, Hamano, Fumie, Yasuda, Megumi, Okamura, Tadashi, Shindou, Hideo, Shimizu, Takao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481256/ https://www.ncbi.nlm.nih.gov/pubmed/32891885 http://dx.doi.org/10.1016/j.isci.2020.101495 |
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