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Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

A unique, protective cell envelope contributes to the broad drug resistance of the nosocomial pathogen Acinetobacter baumannii. Here we use transposon insertion sequencing to identify A. baumannii mutants displaying altered susceptibility to a panel of diverse antibiotics. By examining mutants with...

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Detalles Bibliográficos
Autores principales: Geisinger, Edward, Mortman, Nadav J., Dai, Yunfei, Cokol, Murat, Syal, Sapna, Farinha, Andrew, Fisher, Delaney G., Tang, Amy Y., Lazinski, David W., Wood, Stephen, Anthony, Jon, van Opijnen, Tim, Isberg, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481262/
https://www.ncbi.nlm.nih.gov/pubmed/32908144
http://dx.doi.org/10.1038/s41467-020-18301-2