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Halogenation as a tool to tune antimicrobial activity of peptoids

Antimicrobial peptides have attracted considerable interest as potential new class of antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is limited, in part due to susceptibility towards enzymatic degradation and low bioavailability. Peptoids (oligomers of N-subs...

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Detalles Bibliográficos
Autores principales: Molchanova, Natalia, Nielsen, Josefine Eilsø, Sørensen, Kristian B., Prabhala, Bala Krishna, Hansen, Paul Robert, Lund, Reidar, Barron, Annelise E., Jenssen, Håvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481290/
https://www.ncbi.nlm.nih.gov/pubmed/32908179
http://dx.doi.org/10.1038/s41598-020-71771-8