Cargando…

Halogenation as a tool to tune antimicrobial activity of peptoids

Antimicrobial peptides have attracted considerable interest as potential new class of antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is limited, in part due to susceptibility towards enzymatic degradation and low bioavailability. Peptoids (oligomers of N-subs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Molchanova, Natalia, Nielsen, Josefine Eilsø, Sørensen, Kristian B., Prabhala, Bala Krishna, Hansen, Paul Robert, Lund, Reidar, Barron, Annelise E., Jenssen, Håvard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481290/ https://www.ncbi.nlm.nih.gov/pubmed/32908179 http://dx.doi.org/10.1038/s41598-020-71771-8

Ejemplares similares

Anti-persister and Anti-biofilm Activity of Self-Assembled Antimicrobial Peptoid Ellipsoidal Micelles
por: Lin, Jennifer S., et al.
Publicado: (2022)

Real‐Time Monitoring of Multitarget Antimicrobial Mechanisms of Peptoids Using Label‐Free Imaging with Optical Diffraction Tomography
por: Kim, Minsang, et al.
Publicado: (2023)

Real‐Time Monitoring of Multitarget Antimicrobial Mechanisms of Peptoids Using Label‐Free Imaging with Optical Diffraction Tomography (Adv. Sci. 24/2023)
por: Kim, Minsang, et al.
Publicado: (2023)

Membrane‐acting biomimetic peptoids against visceral leishmaniasis
por: Kumar, Vivek, et al.
Publicado: (2023)

Efficacy of Cathelicidin-Mimetic Antimicrobial Peptoids against Staphylococcus aureus
por: Benjamin, Aaron B., et al.
Publicado: (2022)

In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents
por: Czyzewski, Ann M., et al.
Publicado: (2016)

Molecular Transport and Growth of Lipid Vesicles Exposed to Antimicrobial Peptides
por: Nielsen, Josefine Eilsø, et al.
Publicado: (2021)

Structure-Activity Study of an All-d Antimicrobial Octapeptide D2D
por: Lone, Abdullah, et al.
Publicado: (2019)

Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids
por: Diamond, Gill, et al.
Publicado: (2021)

Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients
por: Molchanova, Natalia, et al.
Publicado: (2019)

Structure–Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues
por: Greco, Ines, et al.
Publicado: (2019)

Lipid membrane interactions of self-assembling antimicrobial nanofibers: effect of PEGylation
por: Nielsen, Josefine Eilsø, et al.
Publicado: (2020)

Synthesis of Peptoids Containing Multiple Nhtrp and Ntrp Residues: A Comparative Study of Resin, Cleavage Conditions and Submonomer Protection
por: Lone, Abdullah, et al.
Publicado: (2020)

A Readily Applicable Strategy to Convert Peptides to Peptoid-based Therapeutics
por: Park, Minyoung, et al.
Publicado: (2013)

Current State of SLC and ABC Transporters in the Skin and Their Relation to Sweat Metabolites and Skin Diseases
por: Nielsen, Marcus M. K., et al.
Publicado: (2021)

Ultra-Short Antimicrobial Peptoids Show Propensity for Membrane Activity Against Multi-Drug Resistant Mycobacterium tuberculosis
por: Khara, Jasmeet Singh, et al.
Publicado: (2020)

Antibiofilm Peptides and Peptidomimetics with Focus on Surface Immobilization
por: Andrea, Athina, et al.
Publicado: (2018)

Peptoids successfully inhibit the growth of gram negative E. coli causing substantial membrane damage
por: Mojsoska, Biljana, et al.
Publicado: (2017)

Intracellular biomass flocculation as a key mechanism of rapid bacterial killing by cationic, amphipathic antimicrobial peptides and peptoids
por: Chongsiriwatana, Nathaniel P., et al.
Publicado: (2017)

Accelerating Lipid Flip-Flop at Low Concentrations: A General Mechanism for Membrane Binding Peptides
por: Carrer, Manuel, et al.
Publicado: (2023)

Optimizing Exogenous Surfactant as a Pulmonary Delivery Vehicle for Chicken Cathelicidin-2
por: Baer, Brandon, et al.
Publicado: (2020)

Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis
por: Aloul, Karim M., et al.
Publicado: (2022)

Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides
por: Greco, Ines, et al.
Publicado: (2020)

Review: Structure-Activity Relationship of Antimicrobial Peptoids
por: Nyembe, Priscilla L., et al.
Publicado: (2023)

Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity
por: Huang, Wei, et al.
Publicado: (2014)

Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections
por: Greco, Ines, et al.
Publicado: (2019)

Publisher Correction: Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections
por: Greco, Ines, et al.
Publicado: (2019)

In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma
por: Greco, Ines, et al.
Publicado: (2018)

Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins
por: Czyzewski, Ann M., et al.
Publicado: (2018)

Isolation, Purification, and Antimicrobial Characterization of Cannabidiolic Acid and Cannabidiol from Cannabis sativa L.
por: Martinenghi, Laura Daniela, et al.
Publicado: (2020)

Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs
por: Molchanova, Natalia, et al.
Publicado: (2017)

Peptides and Peptidomimetics for Antimicrobial Drug Design
por: Mojsoska, Biljana, et al.
Publicado: (2015)

The Immunogenicity of Peptoid-Protein Conjugates
por: Case, Allison, et al.
Publicado: (2016)

Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry
por: Fürniss, Daniel, et al.
Publicado: (2013)

Folding of unstructured peptoids and formation of hetero-bimetallic peptoid complexes upon side-chain-to-metal coordination
por: Baskin, Maria, et al.
Publicado: (2018)

Chain-End Modifications and Sequence Arrangements of Antimicrobial Peptoids for Mediating Activity and Nano-Assembly
por: Hasan, Abshar, et al.
Publicado: (2020)

The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus
por: Gottschalk, Sanne, et al.
Publicado: (2013)

Blood biomarker for Parkinson disease: peptoids
por: Yazdani, Umar, et al.
Publicado: (2016)

Recent Advances in the Synthesis of Peptoid Macrocycles
por: Webster, Alexandra M., et al.
Publicado: (2018)

Self-Assembly of Minimal Peptoid Sequences
por: Castelletto, Valeria, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3fqtbuv3n8q5u5dgn122qbtpja