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TLR4 Signaling by Heme and the Role of Heme-Binding Blood Proteins

Toll-like receptors (TLRs), also known as pattern recognition receptors, respond to exogenous pathogens and to intrinsic danger signals released from damaged cells and tissues. The tetrapyrrole heme has been suggested to be an agonist for TLR4, the receptor for the pro-inflammatory bacterial compone...

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Detalles Bibliográficos
Autores principales: Janciauskiene, Sabina, Vijayan, Vijith, Immenschuh, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481328/
https://www.ncbi.nlm.nih.gov/pubmed/32983129
http://dx.doi.org/10.3389/fimmu.2020.01964