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Klotho, Aging, and the Failing Kidney

Klotho has been recognized as a gene involved in the aging process in mammals for over 30 years, where it regulates phosphate homeostasis and the activity of members of the fibroblast growth factor (FGF) family. The α-Klotho protein is the receptor for Fibroblast Growth Factor-23 (FGF23), regulating...

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Detalles Bibliográficos
Autores principales: Buchanan, Sarah, Combet, Emilie, Stenvinkel, Peter, Shiels, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481361/
https://www.ncbi.nlm.nih.gov/pubmed/32982966
http://dx.doi.org/10.3389/fendo.2020.00560