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Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains

Despite high vaccination coverage, Bordetella pertussis the causative agent of whooping cough is still a health concern worldwide. A resurgence of pertussis cases has been reported, particularly in countries using acellular vaccines with waning immunity and pathogen adaptation thought to be responsi...

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Detalles Bibliográficos
Autores principales: Lesne, Elodie, Cavell, Breeze E., Freire-Martin, Irene, Persaud, Ruby, Alexander, Frances, Taylor, Stephen, Matheson, Mary, van Els, Cécile A. C. M., Gorringe, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481377/
https://www.ncbi.nlm.nih.gov/pubmed/32983069
http://dx.doi.org/10.3389/fmicb.2020.02108