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PARK2 promotes mitochondrial pathway of apoptosis and antimicrotubule drugs chemosensitivity via degradation of phospho-BCL-2

Rationale: Neoadjuvant chemotherapy has become the standard treatment of locally advanced breast cancer. Antimicrotubule drugs and DNA-damaging drugs are the most popular medicines used for neoadjuvant chemotherapy. However, we are unable to predict which chemotherapeutic drug will benefit to an ind...

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Detalles Bibliográficos
Autores principales: Chen, Hengxing, Li, Yun, Li, Yu, Chen, Zhen, Xie, Limin, Li, Wenjia, Zhu, Yuanxin, Xue, Hong, Koeffler, H. Phillip, Wu, Wenjing, Hu, Kaishun, Yin, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481404/
https://www.ncbi.nlm.nih.gov/pubmed/32929329
http://dx.doi.org/10.7150/thno.47044