Lack of FGF21 promotes NASH-HCC transition via hepatocyte-TLR4-IL-17A signaling

Rationale: Hepatocellular carcinoma (HCC) has been increasingly recognized in nonalcoholic steatohepatitis (NASH) patients. Fibroblast growth factor 21 (FGF21) is reported to prevent NASH and delay HCC development. In this study, the effects of FGF21 on NASH progression and NASH-HCC transition and t...

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Detalles Bibliográficos
Autores principales: Zheng, Qianqian, Martin, Robert C., Shi, Xiaoju, Pandit, Harshul, Yu, Youxi, Liu, Xingkai, Guo, Wei, Tan, Min, Bai, Ou, Meng, Xin, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481424/
https://www.ncbi.nlm.nih.gov/pubmed/32929325
http://dx.doi.org/10.7150/thno.45988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481424/
https://www.ncbi.nlm.nih.gov/pubmed/32929325
http://dx.doi.org/10.7150/thno.45988

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