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Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells

Background: Oxidative stress from elevated reactive oxygen species (ROS) has been reported to induce cell apoptosis and may provide a means to target cancer cells. Celastrol is a natural bioactive compound that was recently shown to increase ROS levels and cause apoptosis in cancer cells. However, t...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Zhao, Ying, Luo, Wu, Chen, Sian, Lin, Feng, Zhang, Xi, Fan, Shijie, Shen, Xian, Wang, Yi, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481428/
https://www.ncbi.nlm.nih.gov/pubmed/32929349
http://dx.doi.org/10.7150/thno.46728