Single-cell transcriptomes of pancreatic preinvasive lesions and cancer reveal acinar metaplastic cells’ heterogeneity

Acinar metaplasia is an initial step in a series of events that can lead to pancreatic cancer. Here we perform single-cell RNA-sequencing of mouse pancreas during the progression from preinvasive stages to tumor formation. Using a reporter gene, we identify metaplastic cells that originated from aci...

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Detalles Bibliográficos
Autores principales: Schlesinger, Yehuda, Yosefov-Levi, Oshri, Kolodkin-Gal, Dror, Granit, Roy Zvi, Peters, Luriano, Kalifa, Rachel, Xia, Lei, Nasereddin, Abdelmajeed, Shiff, Idit, Amran, Osher, Nevo, Yuval, Elgavish, Sharona, Atlan, Karine, Zamir, Gideon, Parnas, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481797/
https://www.ncbi.nlm.nih.gov/pubmed/32908137
http://dx.doi.org/10.1038/s41467-020-18207-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481797/
https://www.ncbi.nlm.nih.gov/pubmed/32908137
http://dx.doi.org/10.1038/s41467-020-18207-z

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