Switchable foldamer ion channels with antibacterial activity

Synthetic ion channels may have applications in treating channelopathies and as new classes of antibiotics, particularly if ion flow through the channels can be controlled. Here we describe triazole-capped octameric α-aminoisobutyric acid (Aib) foldamers that “switch on” ion channel activity in phos...

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Detalles Bibliográficos
Autores principales: Peters, Anna D., Borsley, Stefan, della Sala, Flavio, Cairns-Gibson, Dominic F., Leonidou, Marios, Clayden, Jonathan, Whitehead, George F. S., Vitórica-Yrezábal, Iñigo J., Takano, Eriko, Burthem, John, Cockroft, Scott L., Webb, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481839/
https://www.ncbi.nlm.nih.gov/pubmed/32953034
http://dx.doi.org/10.1039/d0sc02393k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481839/
https://www.ncbi.nlm.nih.gov/pubmed/32953034
http://dx.doi.org/10.1039/d0sc02393k

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