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Intralesional Injection of Mouse Mesenchymal Stem Cells Reduces IL-10 Production and Parasite Burden in L. major Infected BALB/c Mice

OBJECTIVE: Leishmaniasis is of public health problems, especially in endemic areas. The activation of macrophages, as the main host of leishmania and promotion of the TH1 immune responses, are the main goal of im-munotherapy methods. Recently, the immunomodulatory role of mesenchymal stem cells (MSC...

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Detalles Bibliográficos
Autores principales: Zanganeh, Elham, Soudi, Sara, Hosseini, Ahmad Zavaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481897/
https://www.ncbi.nlm.nih.gov/pubmed/32779429
http://dx.doi.org/10.22074/cellj.2020.6838