Nicotinamide Phosphoribosyltransferase Knockdown Leads to Lipid Accumulation in HepG2 Cells through The SIRT1-AMPK Pathway

OBJECTIVE: Nicotinamide phosphoribosyltransferase (NAMPT), which is responsible for biosynthesis of nicotinamide adenine dinucleotide (NAD), has a regulatory role in cellular metabolism and thus, might be implicated in non-alcoholic fatty liver disease (NAFLD). This study aimed to show how NAMPT dow...

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Detalles Bibliográficos
Autores principales: Ilbeigi, Davod, Nourbakhsh, Mitra, Pasalar, Parvin, Meshkani, Reza, Shokri Afra, Hajar, Panahi, Ghodratollah, Borji, Mohammad, Sharifi, Roya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481905/
https://www.ncbi.nlm.nih.gov/pubmed/32779442
http://dx.doi.org/10.22074/cellj.2020.7013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481905/
https://www.ncbi.nlm.nih.gov/pubmed/32779442
http://dx.doi.org/10.22074/cellj.2020.7013

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