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In Vivo Structural and Functional Abnormalities of the Striatums Is Related to Decreased Astrocytic BDNF in Itpr2(−/−) Mice Exhibiting Depressive-Like Behavior
BACKGROUND: Previous researches indicate that Itpr2(−/−) mice (inositol 1,4,5-trisphosphate receptor type 2 knockout mice) show depressive-like symptoms; however, little is known regarding the in vivo neurobiological effect of Itpr2 as well as the specific pattern of brain abnormalities in Itpr2(−/−...
Autores principales: | Zeng, Shanmei, Liu, Kai, Zhang, Jingyu, Chen, Chunhui, Xu, Yihua, Wu, Yulan, Deng, Yanjia, Sun, Xuegang, Wen, Ge, Jing, Linlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481938/ https://www.ncbi.nlm.nih.gov/pubmed/32952549 http://dx.doi.org/10.1155/2020/8830670 |
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