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Circuitry and Synaptic Dysfunction in Alzheimer's Disease: A New Tau Hypothesis

For more than five decades, the field of Alzheimer's disease (AD) has focused on two main hypotheses positing amyloid-beta (Aβ) and Tau phosphorylation (pTau) as key pathogenic mediators. In line with these canonical hypotheses, several groups around the world have shown that the synaptotoxicit...

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Detalles Bibliográficos
Autores principales: Mondragón-Rodríguez, Siddhartha, Salgado-Burgos, Humberto, Peña-Ortega, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481966/
https://www.ncbi.nlm.nih.gov/pubmed/32952546
http://dx.doi.org/10.1155/2020/2960343