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Circuitry and Synaptic Dysfunction in Alzheimer's Disease: A New Tau Hypothesis
For more than five decades, the field of Alzheimer's disease (AD) has focused on two main hypotheses positing amyloid-beta (Aβ) and Tau phosphorylation (pTau) as key pathogenic mediators. In line with these canonical hypotheses, several groups around the world have shown that the synaptotoxicit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481966/ https://www.ncbi.nlm.nih.gov/pubmed/32952546 http://dx.doi.org/10.1155/2020/2960343 |