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PML-RARA Fusion Transcripts Detectable 8 Months prior to Promyelocytic Blast Crisis in Chronic Myeloid Leukemia

Promyelocytic blast crisis arising from chronic myeloid leukemia (CML) is rare. We present a 40-year-old male who developed promyelocytic blast crisis 17 months after CML diagnosis, confirmed by the presence of the t(15;17) and t(9;22) translocations in the leukemic cells. Preserved nucleic acids fr...

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Detalles Bibliográficos
Autores principales: Wolanin, Stephanie, McCall, Robert K., Pettenati, Mark J., Beaty, Michael W., Insuasti-Beltran, Giovanni, Powell, Bayard L., O'Neill, Stacey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481999/
https://www.ncbi.nlm.nih.gov/pubmed/32953185
http://dx.doi.org/10.1155/2020/8830595