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Live-Cell FRET Reveals that Malaria Nutrient Channel Proteins CLAG3 and RhopH2 Remain Associated throughout Their Tortuous Trafficking

Malaria parasites increase their host erythrocyte’s permeability to various nutrients, fueling intracellular pathogen development and replication. The plasmodial surface anion channel (PSAC) mediates this uptake and is linked to the parasite-encoded RhopH complex, consisting of CLAG3, RhopH2, and Rh...

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Detalles Bibliográficos
Autores principales: Ahmad, Moaz, Manzella-Lapeira, Javier, Saggu, Gagandeep, Ito, Daisuke, Brzostowski, Joseph A., Desai, Sanjay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482060/
https://www.ncbi.nlm.nih.gov/pubmed/32900800
http://dx.doi.org/10.1128/mBio.01354-20