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Live-Cell FRET Reveals that Malaria Nutrient Channel Proteins CLAG3 and RhopH2 Remain Associated throughout Their Tortuous Trafficking
Malaria parasites increase their host erythrocyte’s permeability to various nutrients, fueling intracellular pathogen development and replication. The plasmodial surface anion channel (PSAC) mediates this uptake and is linked to the parasite-encoded RhopH complex, consisting of CLAG3, RhopH2, and Rh...
Autores principales: | Ahmad, Moaz, Manzella-Lapeira, Javier, Saggu, Gagandeep, Ito, Daisuke, Brzostowski, Joseph A., Desai, Sanjay A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482060/ https://www.ncbi.nlm.nih.gov/pubmed/32900800 http://dx.doi.org/10.1128/mBio.01354-20 |
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