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The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site

Plasmodium falciparum RH5 is a secreted parasite ligand that is essential for erythrocyte invasion through direct interaction with the host erythrocyte receptor basigin. RH5 forms a tripartite complex with two other secreted parasite proteins, CyRPA and RIPR, and is tethered to the surface of the pa...

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Detalles Bibliográficos
Autores principales: Campeotto, Ivan, Galaway, Francis, Mehmood, Shahid, Barfod, Lea K., Quinkert, Doris, Kotraiah, Vinayaka, Phares, Timothy W., Wright, Katherine E., Snijders, Ambrosius P., Draper, Simon J., Higgins, Matthew K., Wright, Gavin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482062/
https://www.ncbi.nlm.nih.gov/pubmed/32900802
http://dx.doi.org/10.1128/mBio.01566-20