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The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site
Plasmodium falciparum RH5 is a secreted parasite ligand that is essential for erythrocyte invasion through direct interaction with the host erythrocyte receptor basigin. RH5 forms a tripartite complex with two other secreted parasite proteins, CyRPA and RIPR, and is tethered to the surface of the pa...
Autores principales: | Campeotto, Ivan, Galaway, Francis, Mehmood, Shahid, Barfod, Lea K., Quinkert, Doris, Kotraiah, Vinayaka, Phares, Timothy W., Wright, Katherine E., Snijders, Ambrosius P., Draper, Simon J., Higgins, Matthew K., Wright, Gavin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482062/ https://www.ncbi.nlm.nih.gov/pubmed/32900802 http://dx.doi.org/10.1128/mBio.01566-20 |
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